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Image Search Results
Journal: Journal of Pharmaceutical Analysis
Article Title: Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: Characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
doi: 10.1016/j.jpha.2021.03.014
Figure Lengend Snippet: Comparison of rates of C-2028-GSH S-conjugate formation in RCyt and RLMs. C-2028 (0.05 mM) was incubated with various rat liver subcellular fractions (2 mg/mL) in the presence of GSH (5 mM) over 0, 30, and 60 min. The inset at the top-left corner shows rates of C-2028-GSH S-conjugate formation in RLMs + GSH incubations supplemented with nicotinamide adenine dinucleotide 2'-phosphate tetrasodium salt (NADPH) (1.2 mM) or 1-aminobenzotriazole (1-ABT) (1 mM). Each bar represents the mean ± standard deviation for three independent experiments.
Article Snippet: Acetonitrile (CH 3 CN), methanol (CH 3 OH) (both of gradient grade quality for LC),
Techniques: Incubation, Standard Deviation